Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 22
Filtrar
1.
Cureus ; 16(1): e51772, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38192525

RESUMO

We present the case of an isolated extensor hallucis longus compartment syndrome following a diaphyseal fibular fracture. Our subject underwent syndesmotic fixation and experienced ongoing pain post-procedure. This was associated with an isolated loss of power in extension of the hallux. A diagnosis of an isolated extensor hallucis longus compartment syndrome followed. Our case highlights the vulnerability of this muscle belly to ischemia and reiterates the value of complete clinical examination in the postoperative patient.

2.
World J Orthop ; 15(1): 39-44, 2024 Jan 18.
Artigo em Inglês | MEDLINE | ID: mdl-38293257

RESUMO

BACKGROUND: Total hip arthroplasty (THA) is a common procedure for end stage osteoarthritis. The learning curve for THA is complex and challenging. One of the most difficult skills to master is acetabular reaming. We wish to identify if experience in arthroplasty leads to preservation of more bone stock. AIM: To investigate if increasing surgeon experience will predict an ever decreasing acetabular cup size. METHODS: A retrospective case series of four attending orthopaedic surgeons was completed. All uncemented elective total hip arthroplasties since appointment were selected for inclusion. The size of acetabular cup used was noted and logistic regression was used to identify if a trend to smaller cups existed. RESULTS: A total of 1614 subjects were included with a mean age of 64 years. Overall cups were on average 0.18mm smaller per year (95% confidence interval -0.25 to -0.11, P < 0.001). Individual surgeon trends showed cup sizes to decrease 0.27 mm/year for surgeon A, 0.02 mm/year for surgeon B, 0.15 mm/year for surgeon C and 0.29 mm/year for surgeon D. Three of the four surgeons had a more pronounced trend to smaller cups for male subjects than their female counterparts. CONCLUSION: We found increasing surgeon experience to be associated with an ever-decreasing acetabular cup size. Smaller acetabular cup size may act as a surrogate marker of surgical proficiency by virtue of decreased acetabular reaming.

3.
Ir J Med Sci ; 193(1): 341-343, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-37340226

RESUMO

BACKGROUND: Plain film abdomens (PFA) are frequently used in the emergency department to help guide the management of patients presenting with abdominal symptoms. A plain film abdomen contributes minimally to clinical scenarios due to low sensitivity and specificity. Is a PFA useful in the emergency setting or does it serve to further complicate decision making? AIM: We hypothesise that PFAs in the emergency department are over utilised to falsely reassure clinicians and patients alike. METHODS: A search of the National Integrated Medical Imaging System (NIMIS) database in an Irish tertiary referral hospital was conducted. All plain film abdominal radiographs requested by the emergency department between 01/01/2022 and 31/08/2022 were identified. Requests where there was suspicion of foreign body were excluded. A retrospective search of the NIMIS database identified subjects who underwent subsequent imaging. RESULTS: A total of 619 abdominal films were deemed suitable for inclusion. These comprised of 338 male and 282 female subjects. Subjects had an average age of 64 years. Fifty-seven per cent of PFAs detected no abnormality. Forty-two per cent of subjects had subsequent imaging. The plain film findings correlated with further imaging in only 15% of cases. One case of ruptured aortic aneurysm and 11 perforations were detected on computerised tomography, none of these cases were evident on abdominal X-ray. CONCLUSION: Plain film abdomen requests are over utilised in the emergency department. PFAs are not sensitive for detecting acute pathology and should not be used to decide if a patient requires further imaging or a full clinical assessment.


Assuntos
Abdome , Fluorocarbonos , Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Estudos Retrospectivos , Radiografia Abdominal , Tomografia Computadorizada por Raios X , Serviço Hospitalar de Emergência
4.
Ir J Med Sci ; 192(5): 2243-2249, 2023 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-36715792

RESUMO

BACKGROUND: Fragility fractures are described as fractures resulting from low-energy trauma and are considered diagnostic of reduced bone mineral density or osteoporosis. They often present as hip fractures with hip fractures remaining a common but devastating injury among older patients. Many factors influence a patient's risk of hip fracture and their subsequent risk of death. AIM: In this study, we examined if previous fragility fracture impacts upon mortality after hip fracture. METHODS: This was a retrospective single-center cohort study of patients included in the Irish Hip Fracture registry over a 5-year time period. Epidemiological data including gender, age, type of fracture, type of surgery, bone protection medication, American Society of Anesthetics (ASA) grade, and post-fracture outcomes including death at 30 days and death at 1 year were recorded. The presence or absence of a previous fragility fracture was examined to explore if a previous fragility fracture was an independent predictor of mortality. RESULTS: There were 964 patients included, and 290 of whom had sustained a previous fragility fracture; 289 patients were males and 675 females, 33 patients had died in the 30 days following their surgery, and 180 patients had died within 1 year. We found statistically significant results for gender and age but not for previous fragility fracture influencing mortality (p value 0.230). CONCLUSION: We found that previous fragility fracture does not impact upon mortality in a hip fracture cohort. However, gender and age did impact upon mortality in this study.


Assuntos
Fraturas do Quadril , Osteoporose , Fraturas por Osteoporose , Masculino , Feminino , Humanos , Estados Unidos , Lactente , Estudos Retrospectivos , Estudos de Coortes , Osteoporose/complicações , Osteoporose/epidemiologia , Osteoporose/tratamento farmacológico , Fraturas do Quadril/epidemiologia
5.
Obes Surg ; 25(2): 222-8, 2015 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-25223870

RESUMO

BACKGROUND: Laparoscopic sleeve gastrectomy (SG) is gaining widespread popularity as a definitive bariatric operation that provides satisfactory and durable weight loss as well as comorbidity resolution. Although SG is being increasingly offered to patients of all ages, there is a paucity of reported outcomes in patients ≥62 years of age. The purpose of this study was to perform a comparative analysis of the outcomes of SG in patients >62 years versus a younger age group, with an emphasis on safety and efficacy. METHODS: A retrospective analysis was performed from a prospectively collected database on patients who underwent SG from 2007 to 2012. All patients who were ≥62 years old were compared to those <62 years. RESULTS: There were 182 patients who underwent SG, 17 of whom were ≥62 years old. There were no significant differences in demographics or comorbidity characteristics between the groups. The mean follow-up was 1 year. There was no 30-day mortality in either group. The percent excess weight loss for the younger age group was 44 ± 21 % and the older group was 44 ± 25 %. The percent total body weight loss was 22 ± 10 and 21 ± 10 %, respectively. Weight loss outcomes were maintained for up to 3 years. Comorbidity resolution and improvement rates were equivalent in both groups. CONCLUSIONS: SG is safe and effective in patients ≥62 years. Weight loss and the beneficial effects on comorbidities are equivalent among elderly and younger patients. SG should be offered to elderly patients who are deemed to be appropriate candidates.


Assuntos
Gastrectomia/métodos , Obesidade Mórbida/cirurgia , Cirurgia Bariátrica/métodos , Feminino , Humanos , Laparoscopia , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Resultado do Tratamento , Redução de Peso
6.
Adv Surg ; 48: 201-10, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25293616

RESUMO

The practice of surgery has undergone tumultuous changes over the last 30 years. Disease management, trauma volume, operative techniques, supervision requirements, and allocation of work hours have all changed, resulting in a substantial impact on general surgical training. Changes need to occur in the structure, assessment, and mentorship of future residents to prepare them to enter the marketplace and practice safe medicine with confidence and authority.


Assuntos
Cirurgia Geral/educação , Cirurgia Geral/tendências , Procedimentos Cirúrgicos Ambulatórios/tendências , Competência Clínica , Currículo , Humanos , Internato e Residência , Mentores , Procedimentos Cirúrgicos Minimamente Invasivos/educação , Procedimentos Cirúrgicos Minimamente Invasivos/tendências , Autonomia Profissional , Estados Unidos/epidemiologia , Carga de Trabalho , Ferimentos e Lesões/epidemiologia , Ferimentos e Lesões/cirurgia
7.
J Laparoendosc Adv Surg Tech A ; 24(8): 574-7, 2014 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-25007128

RESUMO

Esophagogastric fistula is a rare complication related to severe inflammation at the gastroesophageal junction. Most causes are related to severe gastroesophageal reflux disease, previous surgery, or malignancy. This is the case of a 72-year-old man who had a laparoscopic Nissen fundoplication. He developed an esophageal obstruction from an intraesophageal pledget. It was removed laparoscopically, and the esophagotomy was buttressed with a Nissen fundoplication. Two months later he developed severe dysphagia, and an esophagogastric fistula was diagnosed. This was a large fistula measuring 20 mm in diameter. A novel hybrid technique was used to divide the fundoplication. Under endoscopic guidance, a 12-mm balloon-tipped trocar was inserted transgastrically. A linear-cutting surgical stapler was used to divide the fundoplication and reopen the gastroesophageal junction. The patient had no further dysphagia or gastroesophageal reflux.


Assuntos
Fístula Esofágica/cirurgia , Fístula Gástrica/cirurgia , Gastroplastia/métodos , Laparoscopia/métodos , Idoso , Transtornos de Deglutição/etiologia , Transtornos de Deglutição/cirurgia , Endoscopia/métodos , Fístula Esofágica/etiologia , Estenose Esofágica/etiologia , Junção Esofagogástrica/cirurgia , Fundoplicatura/efeitos adversos , Fístula Gástrica/etiologia , Refluxo Gastroesofágico/etiologia , Humanos , Masculino , Reoperação , Stents/efeitos adversos
8.
Surg Obes Relat Dis ; 10(4): 654-9, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24708909

RESUMO

BACKGROUND: Patients having previous bariatric surgery are at risk for weight regain and return of co-morbidities. If an anatomic basis for the failure is identified, many surgeons advocate revision or conversion to a Roux-en-Y gastric bypass. The aim of this study was to determine whether revisional bariatric surgery leads to sufficient weight loss and co-morbidity remission. PATIENTS AND METHODS: From 2005-2012, patients undergoing revision were entered into a prospectively maintained database. Perioperative outcomes, including complications, weight loss, and co-morbidity remission, were examined for all patients with a history of a previous vertical banded gastroplasty (VBG) or Roux-en-Y gastric bypass (RYGB). RESULTS: Twenty-two patients with a history of RYGB and 56 with a history of VBG were identified. Following the revisional procedure, the RYGB group experienced 35.8% excess weight loss (%EWL) and a 31.8% morbidity rate. For the VBG group, patients experienced a 46.2% %EWL from their weight before the revisional operation with a 51.8% morbidity rate. Co-morbidity remission rate was excellent. Diabetes (VBG:100%, RYGB: 85.7%), gastroesophageal reflux disease (VBG: 94.4%, RYGB: 80%), and hypertension (VBG: 74.2%, RYGB:60%) demonstrated significant improvement. CONCLUSION: Revision of a failed RYGB or conversion of a VBG to a RYGB provides less weight loss and a higher complication rate than primary RYGB but provides an excellent opportunity for co-morbidity remission.


Assuntos
Derivação Gástrica/efeitos adversos , Refluxo Gastroesofágico/prevenção & controle , Gastroplastia/efeitos adversos , Hipertensão/prevenção & controle , Obesidade Mórbida/cirurgia , Apneia Obstrutiva do Sono/prevenção & controle , Adulto , Índice de Massa Corporal , Feminino , Refluxo Gastroesofágico/etiologia , Humanos , Hipertensão/etiologia , Masculino , Pessoa de Meia-Idade , Obesidade Mórbida/complicações , Reoperação , Estudos Retrospectivos , Apneia Obstrutiva do Sono/etiologia , Resultado do Tratamento , Redução de Peso
9.
Obes Surg ; 24(7): 1052-6, 2014 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-24599874

RESUMO

BACKGROUND: Anastomotic leak at the gastrojejunostomy is a life-threatening complication of laparoscopic Roux-en-Y gastric bypass (LRYGB). Fibrin sealants have been used as topical adjuncts to reduce leaks at the gastrojejunostomy. Our clinical observations suggest that an unintended consequence may be the promotion of anastomotic stricture. We hypothesized that the use of fibrin sealant at the gastrojejunostomy in patients undergoing LRYGB decreases the incidence of anastomotic leak but increases the incidence of clinically significant stricture. METHODS: Following institutional review board approval, medical records of patients undergoing LRYGB by two surgeons at a single institution over a 5-year period were retrospectively reviewed. Preoperative demographics and postoperative complication rates including incidence of gastrojejunostomy leak and endoscopically diagnosed stricture requiring dilation within 1 year of surgery were recorded. RESULTS: Four hundred twenty-five patients had fibrin sealant routinely applied to their gastrojejunostomy site and 104 did not. Four leaks occurred in the sealant group and two leaks occurred in the control group (p = 0.2). Of patients who received sealant, 1.6 % needed postoperative blood transfusion compared to 4.8%of those who did not receive sealant (p=0.05) [corrected]. There was a significantly increased rate of strictures requiring dilation in the sealant group (11.3% compared to 4.8% stricture rate in patients who did not receive sealant, p = 0.04). CONCLUSIONS: In our experience, the use of fibrin sealant at linear stapled gastrojejunostomy site during LRYGB increases the incidence of clinically significant postoperative stricture and does not reduce the incidence of anastomotic leak.


Assuntos
Fístula Anastomótica/prevenção & controle , Adesivo Tecidual de Fibrina/administração & dosagem , Derivação Gástrica/efeitos adversos , Obesidade Mórbida/cirurgia , Complicações Pós-Operatórias/cirurgia , Adesivos Teciduais/administração & dosagem , Constrição Patológica/epidemiologia , Constrição Patológica/etiologia , Transtornos de Deglutição , Desidratação , Feminino , Adesivo Tecidual de Fibrina/efeitos adversos , Humanos , Incidência , Masculino , Seleção de Pacientes , Reoperação , Estudos Retrospectivos , Adesivos Teciduais/efeitos adversos
10.
Int J Oral Maxillofac Implants ; 28(6): 1483-9, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-24278915

RESUMO

PURPOSE: This double-blind randomized controlled trial assessed the effect of subgingival ozone (O3, gaseous ozone, HealOzone MK II, KaVo) and/or hydrogen peroxide (H2O2) on the development of peri-implant mucositis. MATERIALS AND METHODS: Twenty subjects (mean age, 60 ± 7.7 years) with 80 implants (4 implants each) were recruited. First, a 2-week pretrial phase took place to achieve healthy gingiva. Subsequently, partial gum shields were constructed for the experimental area (around the 4 implants); subjects were asked to refrain from brushing in that area by wearing the gum shield. The following treatments were randomly applied (for 60 seconds) to implant sites on days 0, 7, and 14: (1) air (O2) and saline (0.9% NaCl) (control group), (2) O2 and H2O2 (3%), (3) O3 and saline, and (4) O3 and H2O2. Plaque, gingival, and bleeding indices were recorded on days 0, 7, 14, and 21. RESULTS: Significant differences were seen among the treatments (P < .01) in plaque (F = 16.68), modified gingival (F = 7.86), and bleeding (F = 18.42) indices. O3 + saline and O3 + H2O2 produced optimum gingival health scores and were equally effective and the most effective in controlling bleeding (mean score = 0.05), while O2 + saline was the least effective (mean score = 0.56). CONCLUSION: Ozone showed great potential for management of peri-implant mucositis.


Assuntos
Anti-Infecciosos Locais/uso terapêutico , Implantes Dentários/efeitos adversos , Placa Dentária/diagnóstico por imagem , Peróxido de Hidrogênio/uso terapêutico , Mucosite/tratamento farmacológico , Ozônio/uso terapêutico , Idoso , Análise de Variância , Índice de Placa Dentária , Método Duplo-Cego , Feminino , Hemorragia Gengival/prevenção & controle , Gengivite/prevenção & controle , Humanos , Masculino , Pessoa de Meia-Idade , Mucosite/etiologia , Radiografia
11.
J Laparoendosc Adv Surg Tech A ; 23(7): 632-4, 2013 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-23638851

RESUMO

This is a case report of a patient who developed major intestinal complications after the utilization of barbed sutures for an off-label indication. The report serves as a warning for patients and surgeons of the potential injuries that may be caused by the use of new products in unapproved indications.


Assuntos
Volvo Intestinal/etiologia , Intestinos/lesões , Laparoscopia/efeitos adversos , Mesentério/lesões , Suturas/efeitos adversos , Miomectomia Uterina/efeitos adversos , Feminino , Humanos , Doença Iatrogênica , Volvo Intestinal/diagnóstico por imagem , Pessoa de Meia-Idade , Tomografia Computadorizada por Raios X
12.
Surg Endosc ; 26(11): 3163-73, 2012 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-22580877

RESUMO

BACKGROUND: Natural orifice transluminal endoscopic surgery (NOTES) has been mostly performed with the animal under general and inhalational anesthesia (IA-NOTES). To date, NOTES using propofol sedation (PS-NOTES) has not been investigated. This study aimed to assess the feasibility and safety of PS-NOTES for transgastric oophorectomy with carbon dioxide insufflation and to compare its success rates with those of conventional IA-NOTES. METHODS: In this prospective randomized study, NOTES oophorectomy was performed for 19 female dogs randomized to two conditions: PS (study group) and IA (control group). Sedation success rates (ability to visualize and resect ovaries without converting to IA), operative success rates (ability to resect and retrieve both ovaries in full using only NOTES), and vital parameters including hemodynamic and respiratory changes were documented. RESULTS: In the PS-NOTES group (n = 9), the sedation success rate was 100 %. The operative success rate was 67 % (6 of 9 animals) compared with 80 % (8 of 10 animals) in the IA-NOTES group. No purposeful movement occurred during surgical manipulation and no respiratory or cardiovascular complications in occurred the PS group. Heart rate (HR) and end-tidal carbon dioxide (ETCO(2)) were significantly higher in the PS group than in the IA group. Blood pressure (BP) was significantly higher in the PS group only during the middle part of the procedure. Only mild respiratory depression was noted in the PS group, as indicated by elevated but acceptable ETCO(2). Elevations in BP and HR are thought to be related to elevated CO(2) but did not appear to have an adverse impact on the course of the procedure. Recovery was uneventful for all the animals. CONCLUSION: The use of PS-NOTES appears to be feasible, resulting in outcomes comparable with those for IA in dogs. Further studies are needed to determine the applicability of this concept in human NOTES.


Assuntos
Sedação Profunda , Cirurgia Endoscópica por Orifício Natural , Animais , Cães , Estudos de Viabilidade , Feminino , Cirurgia Endoscópica por Orifício Natural/efeitos adversos , Distribuição Aleatória
13.
Cardiol Young ; 21 Suppl 2: 124-32, 2011 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-22152539

RESUMO

Highly sensitised children in need of cardiac transplantation have overall poor outcomes because of increased risk for dysfunction of the cardiac allograft, acute cellular and antibody-mediated rejection, and vasculopathy of the cardiac allograft. Cardiopulmonary bypass and the frequent use of blood products in the operating room and cardiac intensive care unit, as well as the frequent use of homografts, have predisposed potential recipients of transplants to allosensitisation. The expansion in the use of ventricular assist devices and extracorporeal membrane oxygenation has also contributed to increasing rates of allosensitisation in candidates for cardiac transplantation. Antibodies to Human Leukocyte Antigen can be detected before transplantation using several different techniques, the most common being the "complement-dependent lymphocytotoxicity assays". "Solid-phase assays", particularly the "Luminex® single antigen bead method", offer improved specificity and more detailed information regarding specificities of antibodies, leading to improved matching of donors with recipients. Allosensitisation prolongs the time on the waiting list for potential recipients of transplantation and increases the risk of complications and death after transplantation. Aggressive reduction of antibodies to Human Leukocyte Antigen in these high-risk patients is therefore of vital importance for long-term survival of the patient and cardiac allograft. Strategies to decrease Panel Reactive Antibody or percent reactive antibody before transplantation include plasmapheresis, intravenous administration of immunoglobulin, and specific treatment to reduce B-cells, particularly Rituximab. These strategies have resulted in varying degrees of success. Antibody-mediated rejection and cardiac allograft vasculopathy are two of the most important complications of transplantation in patients with high Panel Reactive Antibody. The treatment of antibody-mediated rejection in recipients of cardiac transplants is largely empirical and includes the use of high-dose corticosteroids, plasmapheresis, intravenous administration of immunoglobulins, anti-thymocyte globulin, and Rituximab. Cardiac allograft vasculopathy is believed to be secondary to chronic complement-mediated endothelial injury and chronic vascular rejection. The use of proliferation signal inhibitors, such as sirolimus and everolimus, has been shown to delay the progression of cardiac allograft vasculopathy. In some non-sensitised recipients of cardiac transplants, the de novo formation of antibodies to Human Leukocyte Antigen after transplantation may increase the likelihood of adverse clinical outcomes. The use of serial testing for donor-specific antibodies after cardiac transplantation may be advisable in patients with frequent episodes of rejection and patients with history of sensitisation. Allosensitisation before transplantation can negatively influence outcomes after transplantation. A high incidence of antibody-mediated rejection and graft vasculopathy can result in graft failure and decreased survival. Current strategies to decrease allosensitisation have helped to expand the pool of donors, improve times on the waiting list, and decrease mortality. Centres of transplantation offering desensitisation are currently using plasmapheresis to remove circulating antibodies; intravenous immunoglobulin to inactivate antibodies; cyclophosphamide to suppress B-cell proliferation; and Rituximab to deplete B-lymphocytes. Similar approaches are also used to treat antibody-mediated rejection after transplantation with promising results.


Assuntos
Gerenciamento Clínico , Rejeição de Enxerto , Antígenos HLA/imunologia , Cardiopatias Congênitas/cirurgia , Transplante de Coração/imunologia , Isoanticorpos/imunologia , Cuidados Pré-Operatórios/métodos , Criança , Rejeição de Enxerto/epidemiologia , Rejeição de Enxerto/imunologia , Rejeição de Enxerto/prevenção & controle , Sobrevivência de Enxerto , Cardiopatias Congênitas/imunologia , Teste de Histocompatibilidade , Humanos , Plasmaferese , Fatores de Risco , Taxa de Sobrevida/tendências , Transplante Homólogo , Estados Unidos
14.
Ann Thorac Surg ; 91(4): 1248-54; discussion 1254-5, 2011 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-21440154

RESUMO

BACKGROUND: This manuscript reviews all patients who underwent orthotopic heart transplantations (OHT) at our program (116 patients underwent 119 OHT) to describe their diagnostic characteristics and to assess risk factors for mortality. METHODS: Median age at OHT was 179 days (mean, 1,446.6 ± 188.9 days [4.0 ± 0.5 years]; range, 5 days to 7,125 days [19.5 years]; 15 neonates, 68 infants). Median weight at OHT was 5.5 kg (mean, 17.2 ± 2.1 kg; range, 2.2 to 113 kg). Diagnoses were cardiomyopathy (n = 37), primary transplantation for hypoplastic left heart syndrome (HLHS) or HLHS-related malformation (n = 29), transplantation after prior cardiac surgery for HLHS or HLHS-related malformation (n = 9), non-HLHS congenital heart disease (n = 39), and retransplant (n = 5). RESULTS: Overall Kaplan-Meier 5-year survival was 72.7%. Operative mortality was 12.6% (15 patients). Late mortality was 13.4% (16 patients). Eighty-five patients survived, with a mean follow-up of 5.76 ± 0.48 years (median, 5.1 years; range, 0.12 to 14.0 years). Total follow-up was 507.0 years. No survival difference was seen among the five diagnostic subgroups (p = 0.20). Univariate association between risk factors and survival was assessed for the following variables: age (p = 0.91), weight (p = 0.86), sex (p = 0.47), race (p = 0.40), insurance classification (p = 0.42), high PRA (p = 0.20), pretransplant mechanical circulatory support (p < 0.001), posttransplant mechanical circulatory support (p < 0.001), redo sternotomy (p = 0.07), heterotaxy (p = 0.02), cardiopulmonary bypass time (p = 0.01), and donor heart cross-clamp time (p = 0.02). CONCLUSIONS: Excellent results are expected for children undergoing OHT regardless of diagnostic classification. Pretransplant mechanical circulatory support, posttransplant mechanical circulatory support, cardiopulmonary bypass time, donor heart cross-clamp time, and heterotaxy are risk factors for decreased survival.


Assuntos
Cardiopatias/congênito , Cardiopatias/cirurgia , Transplante de Coração , Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Estudos Prospectivos , Adulto Jovem
15.
Surg Endosc ; 25(6): 1797-801, 2011 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-21136113

RESUMO

BACKGROUND: Symptoms from poorly controlled gastroesophageal reflux disease (GERD) such as heartburn and regurgitation often resolve after laparoscopic Nissen fundoplication. Unfortunately, new gastrointestinal symptoms such as bloating may occur for some patients. Accurate data regarding the gastrointestinal symptoms experienced by patients who have had a laparoscopic fundoplication may help patients to make more informed decisions about pursuing surgery for their reflux disease. METHODS: Patients more than 12 months after a laparoscopic Nissen fundoplication were mailed symptom surveys. Before surgery, all the patients had medically refractory esophageal symptoms (heartburn, regurgitation, or both). Surveys included the Gastrointestinal Quality of Life Index (GIQLI) and questions regarding satisfaction, reintervention, and medication use. Responses for individual GIQLI items were evaluated to determine the gastrointestinal symptoms experienced by fundoplication patients and the relationship of these symptoms to patient satisfaction. RESULTS: Of the 76 patients eligible for inclusion in the survey, 48 returned complete surveys (63%). The mean time since surgery was 28±9 months. No patient experienced frequent regurgitation, and few (10%) reported frequent heartburn at follow-up assessment. No patient required redo fundoplication during the follow-up period. Acid reduction medications were resumed by 25% of the patients, but not all of these patients resumed medications for recurrent GERD symptoms (15% total). After surgery, frequent bloating (21%) and excessive flatus (46%) were often noted. Satisfaction with the results of surgery was high, including 83% of the patients. CONCLUSIONS: Few patients report frequent regurgitation or heartburn after laparoscopic Nissen fundoplication. Although some patients resume acid reduction medications, many do so for reasons other than recurrent GERD symptoms. Most fundoplication patients are quite satisfied with the symptomatic results of surgery, although frequent functional gastrointestinal symptoms are common.


Assuntos
Fundoplicatura/métodos , Satisfação do Paciente , Qualidade de Vida , Adulto , Idoso , Feminino , Azia/epidemiologia , Humanos , Laparoscopia , Masculino , Pessoa de Meia-Idade , Período Pós-Operatório , Resultado do Tratamento , Adulto Jovem
16.
Surgery ; 144(4): 566-72; discussion 572-4, 2008 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-18847640

RESUMO

BACKGROUND: Gastroparesis is characterized by delayed gastric emptying in the absence of obstruction. Common symptoms include nausea, vomiting, and abdominal pain. Severe gastroparesis can result in recurrent hospitalizations, malnutrition, and even death. Gastric electrical stimulation (GES) is a low morbidity treatment that may be effective in patients who are refractory to medical therapy. METHODS: For a period of more than 35 months, 19 GES systems were implanted laparoscopically for refractory gastroparesis of diabetic (DG, n = 10), idiopathic (IG, n = 6), or postsurgical (PSG, n = 3) etiology. Total gastroparesis symptom scores (TSS) and weekly vomiting frequency were assessed. Gastric emptying studies were attained preoperatively and after 6 months. RESULTS: Mean follow-up was 38 weeks. There were no major complications. Within 6 weeks, frequency of vomiting decreased in 75% of DG (6/8) and 100% of IG (4/4) patients. No PSG patient complained of vomiting preoperatively. Mean TSS scores improved significantly at all intervals out to 1 year. Gastric emptying studies normalized in 80% of DG patients but in only 1 of the 6 patients with gastroparesis due to other causes. CONCLUSION: GES therapy can lead to improvement in symptoms of gastroparesis and frequency of vomiting within 6 weeks. This therapy is a low morbidity treatment option that may help patients whose symptoms fail to improve with medical therapy.


Assuntos
Terapia por Estimulação Elétrica/métodos , Gastroparesia/diagnóstico , Gastroparesia/terapia , Qualidade de Vida , Estudos de Coortes , Eletrodos Implantados , Feminino , Seguimentos , Esvaziamento Gástrico/fisiologia , Gastroscopia/métodos , Humanos , Masculino , Satisfação do Paciente , Probabilidade , Medição de Risco , Índice de Gravidade de Doença , Estatísticas não Paramétricas , Resultado do Tratamento
18.
Acta Obstet Gynecol Scand ; 84(1): 7-10, 2005 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-15603560

RESUMO

BACKGROUND: To determine the significance of an inappropriately mature placenta on ultrasound examination (Grannum classification), in a low-risk obstetric population. Scans were performed at 36 weeks' gestation. The study group comprised patients demonstrating a grade III placenta, and the control group comprised patients not demonstrating a grade III placenta. METHODS: A total of 1802 low-risk patients were scanned using serial directed real-time ultrasound at 36 weeks' gestation to determine placental maturity. RESULTS: The incidence of a grade III placenta at 36 weeks' gestation was 3.8% (68/1802). A grade III placenta was associated with young maternal age and cigarette smoking, p < 0.01. The incidence of proteinuric pregnancy-induced hypertension in the study and control groups was 7.4% (5/68) and 1.56% (27/1734), respectively, p < 0.01. The proportion of infants with a weight less than the 10th centile at birth in the study and control groups was 17.6% (12/68) and 5.6% (97/1734), respectively, p < 0.01. CONCLUSIONS: Ultrasound detection of a grade III placenta at 36 weeks' gestation in a low-risk population helps to identify the "at-risk" pregnancy. It helps to predict subsequent development of proteinuric pregnancy-induced hypertension and may help in identifying the growth-restricted baby.


Assuntos
Calcinose/diagnóstico por imagem , Doenças Placentárias/diagnóstico por imagem , Ultrassonografia Pré-Natal , Adulto , Calcinose/epidemiologia , Estudos de Casos e Controles , Feminino , Idade Gestacional , Humanos , Idade Materna , Doenças Placentárias/epidemiologia , Pré-Eclâmpsia/diagnóstico por imagem , Pré-Eclâmpsia/epidemiologia , Gravidez , Resultado da Gravidez , Gravidez de Alto Risco , Estudos Prospectivos , Fatores de Risco , Fumar/epidemiologia
19.
Obstet Gynecol ; 102(4): 845-9, 2003 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-14551017

RESUMO

OBJECTIVE: To investigate the relationship of Helicobacter pylori infection with dyspeptic symptoms in early and late pregnancy. Infection with H pylori and pregnancy outcome were also assessed. METHODS: H pylori seropositivity was determined in 416 antenatal patients at 10 to 14 weeks' gestation. Dyspeptic symptoms were recorded at 10 to 14 weeks' gestation and at 30 to 32 weeks' gestation by means of a well-validated questionnaire. Details of pregnancy outcome were recorded from patients' case notes. RESULTS: The incidence of H pylori infection in our population was 41.8% (164 of 404). Patients infected with H pylori were no more likely than controls to experience dyspepsia at 10 to 14 weeks' or at 30 to 32 weeks' gestation (P =.75 and.43, respectively). CONCLUSION: H pylori infection was not associated with preterm delivery, non reassuring fetal status in labor, or birth weight less than the 10th centile (P =.17,.57, and.19, respectively).H pylori infection is not associated with an increase in dyspepsia or with maternal or neonatal morbidity.


Assuntos
Dispepsia/epidemiologia , Infecções por Helicobacter/epidemiologia , Helicobacter pylori , Complicações Infecciosas na Gravidez/epidemiologia , Adulto , Dispepsia/etiologia , Dispepsia/patologia , Feminino , Infecções por Helicobacter/etiologia , Infecções por Helicobacter/patologia , Humanos , Incidência , Irlanda do Norte/epidemiologia , Gravidez , Complicações Infecciosas na Gravidez/etiologia , Complicações Infecciosas na Gravidez/patologia , Resultado da Gravidez , Primeiro Trimestre da Gravidez , Terceiro Trimestre da Gravidez , Índice de Gravidade de Doença
20.
Gynecol Oncol ; 90(2): 474-7, 2003 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-12893223

RESUMO

BACKGROUND: We describe the discovery, by pathology, of a totally unexpected diagnosis involving an ovarian teratoma. CASE: A middle-aged woman underwent routine total abdominal hysterectomy and bilateral salpingoophrectomy for ultrasonically diagnosed uterine fibroids and a coexistent benign right ovarian cyst. The operative findings were of fibroid uterus and right ovarian teratoma. However, pathology revealed a malignant lymphoma occurring in, and arising from, the teratoma. CONCLUSION: The routine removal of a presumed ovarian teratoma may yield unexpected results. Ovarian teratomas are indeed cellular chimeras.


Assuntos
Linfoma/patologia , Neoplasias Ovarianas/patologia , Teratoma/patologia , Feminino , Humanos , Linfoma/cirurgia , Pessoa de Meia-Idade , Neoplasias Ovarianas/cirurgia , Teratoma/cirurgia
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...